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  Indian J Med Microbiol
 

Figure 1: Pathogenesis of weight loss in cancer cachexia. Etiologies of weight loss in cancer cachexia include nutritional impact symptoms, metabolic changes, and physical impact symptoms, causing reduced intake, tissue wasting, and physical inactivity. They manifest physically and psychosocially. These cause psychosocial burden, including eating- or weight-related distress and social isolation distress. This pathogenesis eventually results in major worse outcomes in cancer cachexia, including poor prognosis, reduced quality of life, and disability. Each item is potentially manageable by multimodal intervention for cancer cachexia

Figure 1: Pathogenesis of weight loss in cancer cachexia. Etiologies of weight loss in cancer cachexia include nutritional impact symptoms, metabolic changes, and physical impact symptoms, causing reduced intake, tissue wasting, and physical inactivity. They manifest physically and psychosocially. These cause psychosocial burden, including eating- or weight-related distress and social isolation distress. This pathogenesis eventually results in major worse outcomes in cancer cachexia, including poor prognosis, reduced quality of life, and disability. Each item is potentially manageable by multimodal intervention for cancer cachexia