Asia-Pacific Journal of Oncology Nursing

REVIEW ARTICLE
Year
: 2021  |  Volume : 8  |  Issue : 6  |  Page : 604--609

Oral Immune-Related Adverse Events – Current Concepts and their Management


Mohamed Faizal Asan, Renita Lorina Castelino, Subhas G Babu, Kumuda Rao, Vaibhav Pandita 
 Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka, India

Correspondence Address:
Renita Lorina Castelino
Department of Oral Medicine and Radiology, Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences, Mangalore, Karnataka
India

Recent advent of immune checkpoint inhibitors (ICIs) have made significant improvement in the treatment outcome of cancer patients. They are also known to increase the overall survival in many malignancies. They target key immune checkpoints, acting on the cytotoxic T-lymphocyte antigen-4, programmed death-1 (PD-1), and PD-1 ligand 1 pathways. ICIs are effective in cancer therapy, but also possess various adverse effects that are termed together as immune-related adverse events (irAEs). Information focusing only on the oral reactions of irAEs is scanty in the literature. Therefore, we performed a computerized database search in PubMed and Google Scholar to identify and collect data regarding the oral adverse effects of ICIs. The early recognition of oral irAEs and appropriative intervention may help in improving the quality of life in patients. This paper presents a brief review of oral irAEs and their management.


How to cite this article:
Asan MF, Castelino RL, Babu SG, Rao K, Pandita V. Oral Immune-Related Adverse Events – Current Concepts and their Management.Asia Pac J Oncol Nurs 2021;8:604-609


How to cite this URL:
Asan MF, Castelino RL, Babu SG, Rao K, Pandita V. Oral Immune-Related Adverse Events – Current Concepts and their Management. Asia Pac J Oncol Nurs [serial online] 2021 [cited 2021 Nov 29 ];8:604-609
Available from: https://www.apjon.org/article.asp?issn=2347-5625;year=2021;volume=8;issue=6;spage=604;epage=609;aulast=Asan;type=0